(2S,4S)-4-Methylglutamic acid
CAS: 6141-27-1
Ref. 3D-FM25845
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Produktinformation
Name:
(2S,4S)-4-Methylglutamic acid
Synonyme:
- (4S)-4-Methyl-L-glutamic Acid
Beschreibung:
(2S,4S)-4-Methylglutamic acid is a synthetic glutamate analog that can bind to the active site of daptomycin. It has been shown to have a higher binding affinity than natural glutamate and is stable at high temperatures. This compound has been evaluated in binding experiments and functional assays against carbapenem-resistant Gram-positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Enterococcus faecium. The synthesis of this compound was achieved by solid-phase synthesis, which used commercially available amino acids. The chemical profile of this analog was also evaluated using various assays, such as uptake assays on retinal neurons. A synthetic scheme was developed for the preparation of this compound.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
161.16 g/mol
Formel:
C6H11NO4
Reinheit:
Min. 95%
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