2-Methylindazole-3-carboxylic acid

CAS: 34252-44-3

Ref. 3D-FM25860

Produktinformation

• Name: 2-Methylindazole-3-carboxylic acid
• Synonyme: 2-Methyl-2H-indazole-3-carboxylic acid

Beschreibung

2-Methylindazole-3-carboxylic acid is a potential impurity in the synthesis of granisetron. It is a byproduct of the reaction between methyl iodide and indazole, which is an unreacted material in the synthesis of 2-methylindazole-3-carboxylic acid. The hydrochloride salt form of granisetron can be obtained by reacting granisetron with hydrochloric acid or hydrogen chloride gas in presence of a base such as triethylamine. 2-Methylindazole-3-carboxylic acid may also be recycled from the reaction mixture. In addition, this compound has been found to be present in low yield in a pharmacopeia for granisetron hydrochloride tablets.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 176.17 g/mol
• Formel: C₉H₈N₂O₂
• Reinheit: Min. 95%