Mevastatin hydroxy acid sodium salt

CAS: 99782-89-5

Ref. 3D-FM25992

Produktinformation

• Name: Mevastatin hydroxy acid sodium salt
• Synonyme: (b-R,?R,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-b,?-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid sodium salt[1S-[1a(b-S*,?S*),2a,8b(R*),8a-a]]-1,2,6,7,8,8a-Hexahydro-b,?-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naph

Beschreibung

Mevastatin is a cholesterol-lowering drug that belongs to the class of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. It is used in the treatment of hypercholesterolemia, which is an excess of cholesterol in the blood. Mevastatin inhibits the biosynthesis of cholesterol by competitively inhibiting HMG-CoA reductase, which is an enzyme involved in the production of mevalonic acid from acetyl-CoA and acetoacetyl-CoA. This drug also inhibits the synthesis of pravastatin through a cytochrome P450 enzyme system. Mevastatin has been shown to inhibit transcriptional regulation in human skin fibroblasts and to downregulate mRNA levels for gene products involved in cellular proliferation.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 430.51 g/mol
• Formel: C₂₃H₃₅NaO₆
• Reinheit: Min. 95%