Produktinformation
Name:Mizolastine
Synonyme:
- 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]- 4(1H)-pyrimidinoneMKC 431Mistamine
Marke:Biosynth
Beschreibung:Mizolastine is a drug that belongs to the class of antihistamines and has been shown to be effective in the treatment of allergic symptoms. Mizolastine is a selective antagonist of H1 receptors, which are located on the surface of cells. It inhibits histamine release from mast cells and thereby relieves allergy symptoms such as sneezing, itching, watery eyes, and runny nose. Mizolastine has a low oral bioavailability because it is rapidly metabolized by the liver. The drug can also cause serious side effects such as skin cancer and bowel disease when used long-term. This drug should not be taken with other drugs that inhibit 2-adrenergic receptors because this may lead to increased cardiovascular adverse events.
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Chemische Eigenschaften
Molekulargewicht:432.49 g/mol
Formel:C24H25FN6O
Reinheit:Min. 95%
Farbe/Form:White/Off-White Solid
InChl:InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)
InChI Key:InChIKey=PVLJETXTTWAYEW-UHFFFAOYSA-N
SMILES:CN(c1nccc(=O)[nH]1)C1CCN(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1