Methyl-4-iodobenzoate

CAS: 619-44-3

Ref. 3D-FM30437

Produktinformation

• Name: Methyl-4-iodobenzoate
• Synonyme: 4-(Carbomethoxy)iodobenzene, 4-(Methoxycarbonyl)-1-iodobenzene, 4-(Methoxycarbonyl)iodobenzene, 4-(Methoxycarbonyl)phenyl iodide, 4-Iodobenzoic acid methyl ester, Benzoic acid, 4-iodo-, methyl ester, Benzoic acid, p-iodo-, methyl ester, Methyl p-iodobenzoate, NSC 9393, p-(Methoxycarbonyl)phenyl iodide, p-Iodobenzoic acid methyl ester

Beschreibung

Methyl-4-iodobenzoate is an organic compound that can be used as a precursor to the synthesis of pemetrexed, a drug that has been shown to be effective against cancer. Methyl-4-iodobenzoate is synthesized by combining 4-iodobenzoic acid with methyl iodide in the presence of sodium azide. The reaction mechanism is thought to involve the formation of an aziridine intermediate and proceeds via a suzuki coupling reaction. This compound can also be synthesized through hydrolysis of methyltriazole and azetidinium chloride with potassium hydroxide, followed by chlorination with hydrochloric acid. Methyl-4-iodobenzoate is soluble in organic solvents such as chloroform and ether, but not in water.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 262.04 g/mol
• Formel: C₈H₇IO₂
• Reinheit: Min. 95%
• Farbe/Form: Powder