5-Methoxypyrazine-2-carboxylic acid

CAS: 40155-42-8

Ref. 3D-FM31315

Produktinformation

• Name: 5-Methoxypyrazine-2-carboxylic acid
• Synonyme: 2-Pyrazinecarboxylic acid, 5-methoxy-, 5-Methoxy-2-pyrazinecarboxylic acid, Pyrazinecarboxylic acid, 5-methoxy-, Pyrazinecarboxylicacid, 5-methoxy-

Beschreibung

5-Methoxypyrazine-2-carboxylic acid (5MPCA) is a diastereoselective inhibitor of β-amyloid peptide aggregation. It has been shown to reduce the formation of β-amyloid in a pharmacodynamic study with significant reduction of Aβ40 and Aβ42 levels in cerebral spinal fluid. 5MPCA inhibits the enzyme β-secretase, which cleaves the amyloid precursor protein (APP) at the β site, leading to reduced production of β-amyloid. The inhibition of β-secretase by 5MPCA prevents Aβ from being generated and thereby reduces its level in cerebral spinal fluid.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 154.12 g/mol
• Formel: C₆H₆N₂O₃
• Reinheit: Min. 95%
• InChl: InChI=1S/C6H6N2O3/c1-11-5-3-7-4(2-8-5)6(9)10/h2-3H,1H3,(H,9,10)
• InChI Key: InChIKey=YVGVOPNUEFTVQO-UHFFFAOYSA-N
• SMILES: COc1cnc(C(=O)O)cn1