4-Methylpyrazole

CAS: 7554-65-6

Ref. 3D-FM36058

Produktinformation

• Name: 4-Methylpyrazole
• Synonyme: Fomepizole, 4-Methyl-1H-pyrazole, 4-Methylpyrazol, 4-Metilpirazol, 4-Mp, Antizol, Pyrazole, 4-methyl-, 1H-Pyrazole, 4-methyl-

Beschreibung

4-Methylpyrazole is a competitive inhibitor of alcohol dehydrogenase, which can be used to treat methanol and ethylene glycol poisoning. It is also used to inhibit the metabolism of ethanol by blocking the conversion of ethanol to acetaldehyde. 4-Methylpyrazole is metabolized into 4-methylpyridinium ion (4MP) by alcohol dehydrogenase, which prevents the conversion of acetaldehyde to acetic acid. This results in an increase in blood levels of acetaldehyde and a decrease in blood levels of acetic acid, leading to an accumulation of toxic metabolites such as formic acid. In addition, 4-methylpyrazole inhibits the enzyme glycol dehydrogenase that breaks down glycols into their harmless components. This leads to an accumulation of toxic intermediate products that are converted back into glycols.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 82.1 g/mol
• Formel: C₄H₆N₂
• Reinheit: Min. 95%
• Farbe/Form: Colorless Powder