Monomethyl fumarate

CAS: 2756-87-8

Ref. 3D-FM40408

Produktinformation

• Name: Monomethyl fumarate
• Synonyme: (2E)-4-methoxy-4-oxobut-2-enoic acid, (2Z)-4-methoxy-4-oxobut-2-enoic acid, (E)-4-Methoxy-4-oxo-but-2-enoic acid, (E)-4-Methoxy-4-oxobut-2-enoic acid, 2-Butenedioic acid (2E)-, 1-methyl ester, 2-Butenedioic acid (2E)-, monomethyl ester, 2-Butenedioic acid (E)-, monomethyl ester, Fumaric acid monomethyl ester, Fumaric acid, methyl ester, Methyl hydrogen fumarate

Beschreibung

Monomethyl fumarate is a metabolite of dimethyl fumarate (DMF) and has been shown to be an inhibitor of the mitochondrial membrane potential. DMF is currently in clinical trials for the treatment of bowel disease, but its use has been limited by its poor oral bioavailability. Monomethyl fumarate has been shown to be more potent than DMF in inhibiting mitochondrial membrane potential and, therefore, may be a better therapeutic candidate for the treatment of bowel disease. Monomethyl fumarate also inhibits cell lysis through inhibition of tiglic acid production and increased resistance to autoimmune diseases.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 130.1 g/mol
• Formel: C₅H₆O₄
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Off-White Powder