4-Nitroacetophenone

CAS: 100-19-6

Ref. 3D-FN03712

Produktinformation

• Name: 4-Nitroacetophenone
• Synonyme: 1-(4-Nitrophenyl)Ethanone, 1-(4-Nitrophenyl)ethan-1-one, 1-Acetyl-4-nitrobenzene, 4'-Nitroacetofenona, 4'-Nitroacetophenon, 4'-Nitroacetophenone, 4-Acetyl-1-nitrobenzene, 4-Acetylnitrobenzene, 4-Nitrophenyl methyl ketone, Acetophenone, 4'-nitro-, Acetophenone, p-nitro-, Ethanone, 1-(4-nitrophenyl)-, Methyl 4-nitrophenyl ketone, Methyl p-nitrophenyl ketone, Nsc 41590, P-Acetylnitrobenzene, P-Nitrophenyl Methyl Ketone

Beschreibung

4-Nitroacetophenone is an organic compound that has been synthesized in an asymmetric synthesis. It is a nitro compound and a radiosensitizer. The chemical structure of 4-Nitroacetophenone is similar to the structure of phenol, with one nitro group and two hydroxyl groups at opposite ends of the molecule. 4-Nitroacetophenone reacts with radiation to produce free radicals that can damage DNA, RNA, and proteins. The reaction mechanism involves the formation of nitrosating agent (R−NO) which interacts with DNA to form a covalent bond between the DNA base and the nitrosating agent. This covalent bond inhibits DNA replication, leading to cell death. 4-Nitroacetophenone has been shown to be effective in inhibiting cell growth in culture by triggering apoptosis in cells treated with high doses of this drug.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 165.15 g/mol
• Formel: C₈H₇NO₃
• Reinheit: Min. 95%
• Farbe/Form: Yellow Powder