Nitrovin

CAS: 804-36-4

Ref. 3D-FN148937

Produktinformation

• Name: Nitrovin
• Synonyme: 1,4-Pentadien-3-one, 1,5-bis(5-nitro-2-furanyl)-, (aminoiminomethyl)hydrazone, 1,5-Bis(5-nitro-2-furyl)-3-pentadienone amidinohydrazone, 1,5-Di(5-Nitro-2-Furyl)Pentadien-3-One Amidinohydrazone Hydrochloride, 1-[[4-(5-Nitro-2-Furyl)-1-[(5-Nitro-2-Furyl)Methyl]But-3-Enylidene]Amino]Guanidine, 2-(1,5-Bis(5-nitrofuran-2-yl)penta-1,4-dien-3-ylidene)hydrazinecarboximidamide, 2-[3-(5-Nitro-2-furanyl)-1-[2-(5-nitro-2-furanyl)ethenyl]-2-propen-1-ylidene]hydrazinecarboximidamide, Biovin 40, Bis(5-nitro-2-furfurylidene)acetone guanylhydrazone, Bis(5-nitrofurfurylidine)acetone guanylhydrazone, Difurazone, Guanidine, [[3-(5-nitro-2-furyl)-1-[2-(5-nitro-2-furyl)vinyl]allylidene]amino]-, Hydrazinecarboximidamide, 2-[3-(5-nitro-2-furanyl)-1-[2-(5-nitro-2-furanyl)ethenyl]-2-propen-1-ylidene]-, Hydrazinecarboximidamide, 2-[3-(5-nitro-2-furanyl)-1-[2-(5-nitro-2-furanyl)ethenyl]-2-propenylidene]-, N''-{(2E)-3-(5-nitrofuran-2-yl)-1-[(E)-2-(5-nitrofuran-2-yl)ethenyl]prop-2-en-1-ylidene}carbonohydrazonic diamide

Beschreibung

Nitrovin is a drug that belongs to the class of pharmacological agents. It is a nitroimidazole derivative that is used as an antibacterial drug. Nitrovin inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Nitrovin also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 360.28 g/mol
• Formel: C₁₄H₁₂N₆O₆
• Reinheit: Min. 95%
• Farbe/Form: Powder