Naphthalene-1-sulfonamide
CAS: 606-25-7
Ref. 3D-FN176411
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Produktinformation
Name:
Naphthalene-1-sulfonamide
Synonyme:
- α-Naphthalenesulfonamide
- 1-Naphthylsulfonamide
- 1-Naphthalenesulfonamide
Beschreibung:
Naphthalene-1-sulfonamide is a growth factor that inhibits the activity of cyclic nucleotide phosphodiesterase. It has been shown to have antiproliferative effects in cancer cells, but its effect on non-cancerous cells is unknown. Naphthalene-1-sulfonamide binds to the active site of cyclic nucleotide phosphodiesterase, which may inhibit the hydrolysis of cAMP and ATP. The binding of naphthalene-1-sulfonamide to cyclic nucleotide phosphodiesterase may also result in an increase in intracellular levels of cAMP and ATP, leading to inhibition of protein kinase A and D activity. This can lead to decreased cellular proliferation, increased apoptosis, or both.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
207.25 g/mol
Formel:
C10H9NO2S
Reinheit:
Min. 95%
InChl:
InChI=1S/C10H9NO2S/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H2,11,12,13)
InChI Key:
InChIKey=ZFIFHAKCBWOSRN-UHFFFAOYSA-N
SMILES:
NS(=O)(=O)c1cccc2ccccc12
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