Nicotinuric acid

CAS: 583-08-4

Ref. 3D-FN26212

Produktinformation

• Name: Nicotinuric acid
• Synonyme: N-(3-Pyridinylcarbonyl)glycine, (Nicotinoylamino)acetic acid, 2-(Nicotinamido)aceticacid, 2-(Nicotinylamino)acetic acid, 2-(Pyridin-3-ylformamido)acetic acid, 2-(Pyridine-3-carbonylamino)acetic acid, 2-[(Pyridin-3-yl)formamido]acetic acid, Glycine, N-(3-pyridinylcarbonyl)-, Glycine, N-nicotinoyl-, N-(pyridin-3-ylcarbonyl)glycine, NSC 71273, Nicotinoyl-glycine, Nicotinoylglycine, Nicotinylglycine, [(Pyridin-3-ylcarbonyl)amino]acetic acid

Beschreibung

Nicotinuric acid is an endogenous metabolite of nicotinic acid, which is a cofactor for the enzyme that catalyzes the conversion of phosphoenolpyruvate to pyruvate. Nicotinuric acid has been shown to be a potential biomarker for human pharmacokinetics. It has been shown to be involved in energy metabolism and may play a role in the pathogenesis of atherosclerotic cardiovascular disease. Nicotinuric acid is also a product of the enzymatic degradation of pyrrolidinecarboxylic acid, which is found in papillary muscle cells and penicillin-binding protein. The formation of nicotinuric acid can be inhibited by nicotinic acid, pyrazinoic acid, or by inhibitors of lc-ms/ms method.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 180.16 g/mol
• Formel: C₈H₈N₂O₃
• Reinheit: Min. 95%
• InChl: InChI=1S/C8H8N2O3/c11-7(12)5-10-8(13)6-2-1-3-9-4-6/h1-4H,5H2,(H,10,13)(H,11,12)
• InChI Key: InChIKey=ZBSGKPYXQINNGF-UHFFFAOYSA-N
• SMILES: O=C(O)CNC(=O)c1cccnc1