N-Nitroso-N-methyl-3-aminopropionic acid, methyl ester

CAS: 383417-47-8

Ref. 3D-FN26378

Produktinformation

• Name: N-Nitroso-N-methyl-3-aminopropionic acid, methyl ester
• Synonyme: 3-(Methylnitrosoamino)-propanoic Acid Methyl Ester, Propanoic acid, 3-(methylnitrosoamino)-, methyl ester, Methyl 3-(methylnitrosoamino)propanoate, β-Alanine, N-methyl-N-nitroso-, methyl ester

Beschreibung

N-Nitroso-N-methyl-3-aminopropionic acid, methyl ester (NMPA) is a carcinogen that is used in the production of butyric acid. NMPA can induce tumors when injected into the liver and lungs of rats. It has also been shown to induce tumorigenesis in the colon, small intestine, and kidney of mice. NMPA is metabolized by decarboxylation to produce n-nitrososarcosine, which damages DNA and inhibits DNA repair. NMPA binds covalently to proteins, forming amino nitroso compounds. These compounds are likely responsible for NMPA's tumorigenic effects.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 146.14 g/mol
• Formel: C₅H₁₀N₂O₃
• Reinheit: Min. 95%
• InChl: InChI=1S/C5H10N2O3/c1-7(6-9)4-3-5(8)10-2/h3-4H2,1-2H3
• InChI Key: InChIKey=NXZQLRDBZJJVLU-UHFFFAOYSA-N
• SMILES: COC(=O)CCN(C)N=O