N-Nitrosopiperazine

CAS: 5632-47-3

Ref. 3D-FN26385

Produktinformation

• Name: N-Nitrosopiperazine
• Synonyme: 1-NitrosopiperazineN-MononitrosopiperazineNSC 50269, N-Mononitrosopiperazine, NSC 50269, NSC 525340, Piperazine, 1-Nitroso-

Beschreibung

N-Nitrosopiperazine is a nitrosating agent that forms N-nitrosamines in the body. It is used to produce anthelmintic drugs, such as albendazole and mebendazole. It is also used to activate aromatic amines. Piperazine reacts with electrophilic nucleophiles by nucleophilic attack at the alpha carbon of the piperazine ring to form substituted piperazines. The reaction proceeds via a S1 mechanism and the rate of formation is proportional to the concentration of substrate and inversely proportional to pH. N-Nitrosopiperazine has been shown to be present in human urine samples, with a formation rate that increases significantly when exposed to acidic conditions. This drug was found to have immunotoxic effects, including induction of chronic oral toxicity, autoimmune diseases, and cancer in rats.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 115.13 g/mol
• Formel: C₄H₉N₃O
• Reinheit: Min. 95%
• Farbe/Form: Slightly Yellow Powder
• InChl: InChI=1S/C4H9N3O/c8-6-7-3-1-5-2-4-7/h5H,1-4H2
• InChI Key: InChIKey=CVTIZMOISGMZRJ-UHFFFAOYSA-N
• SMILES: O=NN1CCNCC1