5-nitro-1,3-benzothiazole

CAS: 2942-07-6

Ref. 3D-FN58973

Produktinformation

• Name: 5-nitro-1,3-benzothiazole
• Synonyme: 1,3-Benzothiazole, 5-Nitro, Benzothiazole, 5-Nitro-

Beschreibung

5-Nitro-1,3-benzothiazole is a cytosolic fluorescent probe that has been shown to be activated by the presence of Ca2+. It has been used in microscopy experiments to study the uptake and distribution of 5-nitro-1,3-benzothiazole in human cervical carcinoma cells. The use of this compound as a fluorescent probe highlights the cytosolic Ca2+ concentration. 5-Nitro-1,3-benzothiazole also shows selectivity for vacuolar versus cytoplasmic Ca2+, with it being more distributed in the latter. This compound is synthesized from nitric acid and benzene through two steps: nitration followed by hydrolysis. The first step produces nitronitrosobenzene, which reacts with hydrogen peroxide to form an intermediate called aestivum. Aestivum then reacts with ammonia to form 5-nitrobenzoic acid which

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 180.18 g/mol
• Formel: C₇H₄N₂SO₂
• Reinheit: Min. 95%