Neuromedin U, rat

CAS: 117505-80-3

Ref. 3D-FN73510

Produktinformation

• Name: Neuromedin U, rat
• Synonyme: Nmu-23 (Rat), Nmu, Rat, Ykvneyqgpvapsggfflfrprn-Nh2, Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-Gly-Gly-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-Nh2, Neuromedin U, H-Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-

Beschreibung

Neuromedin U is a peptide that has been found to have high binding affinity for 5-hydroxytryptamine (5-HT)2 receptors. Neuromedin U is also able to activate locomotor activity in rats, and has been shown to inhibit the growth of mammalian carcinoma cells in culture. This peptide binds to the 5-HT2 receptor and inhibits adenylyl cyclase activity, leading to a decrease in intracellular levels of cAMP and cytosolic Ca2+. The physiological effects of neuromedin U are mediated through its ability to stimulate pluripotent cells in the brain, as well as its ability to inhibit energy metabolism. Neuromedin U has also been shown to bind to polymerase chain reaction (PCR) primers, suggesting it may be used as a probe for DNA sequencing or gene mapping.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 2,642.97 g/mol
• Formel: C₁₂₄H₁₈₀N₃₄O₃₁
• Reinheit: Min. 95%