(5Z)-7-Oxozeaenol

CAS: 66018-38-0

Ref. 3D-FO177760

Produktinformation

• Name: (5Z)-7-Oxozeaenol
• Synonyme: 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,9,10-tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-, (3S,5Z,8S,9S,11E)-, LL-Z 1640-2, F 152, L 783279, (3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione

Beschreibung

(5Z)-7-Oxozeaenol is a natural product that inhibits the transcription factor nuclear factor kappa B (NF-κB) by binding to toll-like receptor 4. It has been shown to inhibit the growth of mesenchymal cells, leading to an increase in markers for epithelial mesenchymal transition. (5Z)-7-Oxozeaenol also induces apoptosis in breast cancer cells, specifically MDA-MB-231 cells. It activates protein kinase A and inhibits protein kinase C. This compound also inhibits the production of vasoactive intestinal peptide and TNF-α. The inhibition of these proteins leads to a decrease in cell growth and proliferation.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 362.37 g/mol
• Formel: C₁₉H₂₂O₇
• Reinheit: Min. 95%