3,4-Pyridine dicarboxylic acid

CAS: 490-11-9

Ref. 3D-FP01987

Produktinformation

• Name: 3,4-Pyridine dicarboxylic acid
• Synonyme: 3,4-Pyridine Dicarboxylic Acid, Chinchomeronic acid, Cinchomeronic Acid Crystalline, Cinchomeronic acid, NSC 178, Pyridine-3,4-Dicarboxylate, Pyridine-3,4-dicarboxylic acid
• CAS: 490-11-9

Beschreibung

3,4-Pyridine dicarboxylic acid is a sodium salt of pyridine-dicarboxylic acid. It has been shown to inhibit the growth of HL-60 cells by binding with copper and inhibiting the activity of 3-hydroxyanthranilic acid in the electron transfer chain. This inhibits cellular respiration and ATP production, which leads to cell death. 3,4-Pyridine dicarboxylic acid binds to picolinic acid by hydrogen bonding interactions and coordinates with copper ions through a geometry that is not ideal for either molecule. This coordination prevents protonation of the carboxylate group on picolinic acid, which disrupts its catalytic activity.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 167.12 g/mol
• Formel: C₇H₅NO₄
• Reinheit: Min. 95%