H-Pro-Ser-Hyp-Gly-Asp-Trp-OH

CAS: 163722-91-6

Ref. 3D-FP109176

Produktinformation

• Name: H-Pro-Ser-Hyp-Gly-Asp-Trp-OH
• Synonyme: PS-Hyp-GDW
• Marke: Biosynth
• Beschreibung: H-Pro-Ser-Hyp-Gly-Asp-Trp-OH is a cyclic hexapeptide with a high activity against platelets. It is an antagonist of the cyclic RGD sequence, which is present in fibrinogen, fibronectin, vitronectin and other proteins. This peptide binds to the n-terminal residue of these proteins and prevents them from binding to their receptors on the surface of platelets. H-Pro-Ser-Hyp-Gly-Asp-Trp-OH has been shown to be specific for human platelets and does not bind to erythrocytes or leukocytes.

Chemische Eigenschaften

• Molekulargewicht: 673.67 g/mol
• Formel: C₃₀H₃₉N₇O₁₁
• Reinheit: Min. 95%
• InChl: InChI=1S/C30H39N7O11/c38-14-22(36-26(43)19-6-3-7-31-19)29(46)37-13-16(39)9-23(37)28(45)33-12-24(40)34-20(10-25(41)42)27(44)35-21(30(47)48)8-15-11-32-18-5-2-1-4-17(15)18/h1-2,4-5,11,16,19-23,31-32,38-39H,3,6-10,12-14H2,(H,33,45)(H,34,40)(H,35,44)(H,36,43)(H,41,42)(H,47,48)/t16-,19+,20+,21+,22+,23+/m1/s1
• InChI Key: InChIKey=VMBYGYPUDBQRRF-KGJIALSRSA-N
• SMILES: O=C(O)C[C@H](NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O