(D-Pro4,D-Trp7·9·10)-Substance P (4-11)

CAS: 86917-57-9

Ref. 3D-FP109336

Produktinformation

• Name: (D-Pro4,D-Trp7·9·10)-Substance P (4-11)
• Synonyme: H-D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2 H-(dP)QQ(dW)F(dW)(dW)M-NH2
• Marke: Biosynth
• Beschreibung: Substance P is a neuropeptide that is found in the central nervous system. It is also found in the gastrointestinal tract and plays a role in the regulation of smooth muscle contraction. Substance P has been shown to be involved in inflammatory responses, immune responses, and regulation of water and electrolyte balance. The maximal response of substance P occurs at concentrations between 0.1 to 1 nM and its inhibitory effect on the apical Ca2+ response occurs at concentrations between 10-100 nM. In addition, substance P has been shown to have an excitatory effect on 5-HT7 receptors with subunit composition GluN1/GluN2A/GluN2B/GluN3A/5-HT7(H).

Chemische Eigenschaften

• Molekulargewicht: 1,207.41 g/mol
• Formel: C₆₂H₇₄N₁₄O₁₀S
• Reinheit: Min. 95%