Pancreastatin (dephosphorylated) (porcine) trifluoroacetate salt

CAS: 106477-83-2

Ref. 3D-FP109742

Produktinformation

• Name: Pancreastatin (dephosphorylated) (porcine) trifluoroacetate salt
• Synonyme: Chromogranin A (240-288) (porcine), Chromogranin A (240-288) (dephosphorylated) (porcine), H-Gly-Trp-Pro-Gln-Ala-Pro-Ala-Met-Asp-Gly-Ala-Gly-Lys-Thr-Gly-Ala-Glu-Glu-Ala-Gln-Pro-Pro-Glu-Gly-Lys-Gly-Ala-Arg-Glu-His-Ser-Arg-Gln-Glu-Glu-Glu-Glu-Glu-Thr-Ala-Gly-Ala-Pro-Gln-Gly-Leu-Phe-Arg-Gly-NH2, Pancreastatin, Porcine
• CAS: 106477-83-2

Beschreibung

Pancreastatin is a cytosolic protein that inhibits the production of peptide hormones such as glucagon, insulin, and gastrin. It is used to treat bowel disease, including carcinoid syndrome and inflammatory bowel disease. Pancreastatin has been shown to inhibit the activity of cyclase enzymes that are responsible for the production of these hormones. Pancreatic beta-cells produce pancreatic polypeptide (PP), which is converted by pancreastatin into inactive PP2. Pancreatic alpha-cells produce somatostatin (SS), which is converted by pancreastatin into inactive SS2. Pancreatic delta cells produce pancreatic polypeptide (PP), which is not affected by pancreastatin. Pancreatic somatostatinomas secrete SS, which is not affected by pancreastatin.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 5,103.39 g/mol
• Formel: C₂₁₄H₃₃₀N₆₈O₇₆S
• Reinheit: Min. 95%