(R)-(-)-Praziquantel

CAS: 57452-98-9

Ref. 3D-FP145531

Produktinformation

• Name: (R)-(-)-Praziquantel
• Synonyme: (11bR)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one

Beschreibung

Praziquantel is a drug used to treat worms in animals. It has been shown to be effective against schistosomiasis, as well as other nematodes and cestodes. Praziquantel is a racemic mixture of two enantiomers, (R)-(-)-praziquantel and (S)-(+)-praziquantel. The former is more active than the latter against Schistosoma mansoni. The praziquantel molecule contains a chiral carbon atom, which makes it optically active. Chloride ions are required for the activity of praziquantel, so urine samples must be treated with dilute hydrochloric acid before use in order to remove them or else the drug will not work properly. Praziquantel can also be used to treat human liver cancer and is effective at doses of 1-2 mg/kg/day.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 312.41 g/mol
• Formel: C₁₉H₂₄N₂O₂
• Reinheit: Min. 95%