4-Phenoxybenzoylchloride

CAS: 1623-95-6

Ref. 3D-FP147538

Produktinformation

• Name: 4-Phenoxybenzoylchloride
• Synonyme: Benzoyl chloride, 4-phenoxy-, Benzoyl chloride, p-phenoxy-, p-Phenoxybenzoyl chloride

Beschreibung

4-phenoxybenzoylchloride is an amide that is used in the industrial production of polymers. It has been used in biological studies to investigate the reaction mechanism of Friedel-Crafts reactions. 4-Phenoxybenzoylchloride can be prepared by reacting biphenyl or diphenyl ether with hydrogen chloride or hydrogen fluoride in the presence of a base such as sodium hydroxide. The Friedel-Crafts acylation reaction involves the addition of an acyl chloride to an aromatic ring, which leads to alkylation of the ring's benzene ring. This reaction can be carried out in a biphasic system consisting of water and organic solvent, with a solid catalyst such as aluminum chloride. Acetaminophen-induced hepatotoxicity is a serious adverse effect that occurs after ingestion of acetaminophen (paracetamol). This toxicity is characterized by necrosis and inflammation, which can lead to liver failure and death.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 232.66 g/mol
• Formel: C₁₃H₉ClO₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C13H9ClO2/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9H
• InChI Key: InChIKey=AOOZVQGGMFGGEE-UHFFFAOYSA-N
• SMILES: O=C(Cl)c1ccc(Oc2ccccc2)cc1