4-Phenoxypiperidine

CAS: 3202-33-3

Ref. 3D-FP147787

Produktinformation

• Name: 4-Phenoxypiperidine
• Synonyme: Piperidine, 4-Phenoxy-

Beschreibung

4-Phenoxypiperidine (4PP) is a potent and selective 5-HT7 receptor antagonist. It has been shown to inhibit the release of acetylcholine, dopamine, histamine and serotonin in rat brain synaptosomes. 4PP also blocks the activation of 5-HT7 receptors by various fatty acids and inhibits the binding of various drugs that interact with 5-ht7 receptors. 4PP has been found to be neuroprotective in mouse models of Parkinson's disease, Alzheimer's disease, and Huntington's disease. 4PP has also been shown to inhibit β-catenin phosphorylation in vitro and block the interaction between β-catenin and H3 receptors in vivo. In addition, it inhibits the activity of protein kinase A and protein kinase C, which have been implicated in neurodegenerative diseases.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 177.24 g/mol
• Formel: C₁₁H₁₅NO
• Reinheit: Min. 95%
• InChl: InChI=1S/C11H15NO/c1-2-4-10(5-3-1)13-11-6-8-12-9-7-11/h1-5,11-12H,6-9H2
• InChI Key: InChIKey=KBYPITRKIJKGMD-UHFFFAOYSA-N
• SMILES: c1ccc(OC2CCNCC2)cc1