7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylicacid

CAS: 1016241-64-7

Ref. 3D-FP148379

Produktinformation

• Name: 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylicacid
• CAS: 1016241-64-7

Beschreibung

7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylicacid is a kinase inhibitor that inhibits the cyclin-dependent kinases. It is used in the treatment of breast and lung cancer. 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylicacid has been shown to inhibit the activity of pyrimidine kinases with IC50 values of 0.5 μM for ab1 and 0.8 μM for cdk1. This drug also inhibits the activity of succinate salt hydrate (SSH) with IC50 values of 1 μM for ab1, 2 μM for cdk1, and 4 μM for cdk2/cyclin E. 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid also inhibits pancreatic cancer cells in culture with an IC50

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 163.13 g/mol
• Formel: C₇H₅N₃O₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C7H5N3O2/c11-7(12)5-1-4-2-8-3-9-6(4)10-5/h1-3H,(H,11,12)(H,8,9,10)
• InChI Key: InChIKey=HHZKYTGSMOMGOQ-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc2cncnc2[nH]1