Patuletin

CAS: 519-96-0

Ref. 3D-FP157207

Produktinformation

• Name: Patuletin
• Synonyme: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-6-methoxy-4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-6-methoxy-4H-chromen-4-one, 3,3′,4′,5,7-Pentahydroxy-6-methoxyflavone, 3,5,7,3′,4′-Pentahydroxy-6-methoxyflavone, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-6-methoxy-, 6-Methoxyquercetin, Flavone, 3,3′,4′,5,7-pentahydroxy-6-methoxy-, Petuletin, Quercetagetin 6-methyl ether

Beschreibung

Patuletin is a natural compound that belongs to the group of sesquiterpene lactones. Patuletin has been shown to have cytotoxic and anti-inflammatory properties in vitro. Patuletin induces cell lysis by binding to nuclear DNA, which blocks transcription and replication of cellular DNA. Patuletin also inhibits the growth of 3T3-L1 preadipocytes by reducing the production of p-hydroxybenzoic acid (PHBA) from tyrosine. This PHBA acts as a cofactor for the enzyme phenylalanine hydroxylase, which catalyzes conversion of tyrosine to PHBA. In addition, patuletin may inhibit protein synthesis by interfering with signal pathways such as MAPK/ERK and PI3K/Akt signaling.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 332.26 g/mol
• Formel: C₁₆H₁₂O₈
• Reinheit: 80%
• Farbe/Form: White Powder