Polmacoxib
CAS: 301692-76-2
Ref. 3D-FP172578
2mg | 136,00 € | ||
5mg | 217,00 € | ||
10mg | 346,00 € | ||
25mg | 542,00 € | ||
50mg | 775,00 € |
Produktinformation
- Acelex
Polmacoxib is a cox-2 inhibitor that binds to the enzyme cyclooxygenase-2 (COX-2), preventing the formation of prostaglandins. It is a monoclonal antibody that blocks the production of chemokines, which are cytokines that attract inflammatory cells to sites of injury and infection. Polmacoxib shows good pharmacokinetic properties with a half-life of approximately 16 hours. Urine samples show polmacoxib as intact drug, with no metabolites detected. In animal studies, polmacoxib has been shown to have anti-inflammatory and analgesic effects similar to nonsteroidal anti-inflammatory drugs (NSAIDs). Polmacoxib may also be used in combination with other drugs as an injection solution to prevent or treat inflammation, pain, and fever. Polmacoxib has been shown to inhibit tumor necrosis factor related apoptosis inducing factor (TRAIL) induced apoptosis in human colon cancer cells.
Chemische Eigenschaften
Technische Anfrage zu: 3D-FP172578 Polmacoxib
Wenn Sie ein Angebot anfordern oder eine Bestellung aufgeben möchten, legen Sie stattdessen die gewünschten Produkte in Ihren Warenkorb und fordern Sie dann ein Angebot oder eine Bestellung an aus dem Warenkorb. Es ist schneller, billiger und Sie können von den verfügbaren Rabatten und anderen Vorteilen profitieren.