Prazobind

CAS: 107021-36-3

Ref. 3D-FP27127

Produktinformation

• Name: Prazobind
• Synonyme: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5-dienyl-carbonyl)-piperazineSZL-49
• Marke: Biosynth
• Beschreibung: Prazobind is an irreversible inhibitor of the enzyme phosphodiesterase 3. This drug inhibits the degradation of cyclic AMP, which leads to increased intracellular levels of Ca2+. Prazobind has been shown to have a beneficial effect on liver cells and phenoxybenzamine-induced hypertension in rats. The kinetic data obtained from polymerase chain reaction studies show that Prazobind has a high affinity for polymerase enzymes with a low dissociation constant. This drug also inhibits transcription and replication by binding to the active site of RNA polymerase. It also produces an increase in proximal tubule Ca2+ influx and glomerular filtration rate in rats, which may be due to reactive functional groups present in the drug.

Chemische Eigenschaften

• Molekulargewicht: 421.49 g/mol
• Formel: C₂₃H₂₇N₅O₃
• Reinheit: Min. 95%
• Farbe/Form: White to off-white solid.