Primaquine diphosphate

CAS: 63-45-6

Ref. 3D-FP27162

Produktinformation

• Name: Primaquine diphosphate
• Synonyme: N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine Phosphate
• Marke: Biosynth
• Beschreibung: Primaquine is an antimalarial drug that belongs to the class of natural compounds. It works by inhibiting the activity of blood cells and preventing malaria parasites from reproducing in the red blood cells. Primaquine diphosphate (PQDP) is a recombinant cytochrome P450 enzyme that has been shown to have high activity against Mycobacterium tuberculosis and other bacteria. PQDP is a strong inhibitor of cytochrome P450 enzymes, which are involved in drug metabolism, leading to serious drug interactions with many drugs such as warfarin, phenytoin, or oral contraceptives. This recombinant enzyme also has been shown to bind to toll-like receptor 2 (TLR2) on macrophages and monocytes, which can lead to inflammation in the bowel.

Chemische Eigenschaften

• Molekulargewicht: 455.34 g/mol
• Formel: C₁₅H₂₇N₃O₉P₂
• Farbe/Form: Powder
• InChl: InChI=1S/C15H21N3O.2H3O4P/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14;2*1-5(2,3)4/h4,6,8-11,18H,3,5,7,16H2,1-2H3;2*(H3,1,2,3,4)
• InChI Key: InChIKey=GJOHLWZHWQUKAU-UHFFFAOYSA-N
• SMILES: COc1cc(NC(C)CCCN)c2ncccc2c1.O=P(O)(O)O.O=P(O)(O)O