Propanedioic acid 1-methyl ester

CAS: 16695-14-0

Ref. 3D-FP32631

Produktinformation

• Name: Propanedioic acid 1-methyl ester
• Synonyme: Methyl hydrogen malonateMonomethyl malonate, Aurora Ka-6464, Methyl hydrogen malonate

Beschreibung

Propanedioic acid 1-methyl ester (PDM) is a synthetic trifluoroacetic acid ester of the natural fatty acid, propanedioic acid. It has been found to be a potent inhibitor of the enzyme malonic acid decarboxylase in vitro and has also been shown to inhibit the production of prostaglandin E2 in mice with adjuvant arthritis. PDM is used as a diagnostic agent for autoimmune diseases and inflammatory diseases. It is also being studied as an anti-inflammatory drug for use in the treatment of chronic inflammatory conditions such as rheumatoid arthritis, psoriasis, and ulcerative colitis. The mechanism of action is not well understood but may involve inhibition of arachidonic acid metabolism or inhibition of cyclooxygenase enzymes.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 118.09 g/mol
• Formel: C₄H₆O₄
• Reinheit: Min. 95%
• Farbe/Form: Colourless To Pale Yellow Clear Liquid
• InChl: InChI=1S/C4H6O4/c1-8-4(7)2-3(5)6/h2H2,1H3,(H,5,6)
• InChI Key: InChIKey=PBVZQAXFSQKDKK-UHFFFAOYSA-N
• SMILES: COC(=O)CC(=O)O