Z-Phe-Arg-AMC·HCl

CAS: 65147-22-0

Ref. 3D-FP47305

Produktinformation

• Name: Z-Phe-Arg-AMC·HCl
• Synonyme: Purity Limit? 99% (TLC), 3095V, 5: PN: WO2004106541 PAGE: 15 claimed protein, <span class="text-smallcaps">L</smallcap>-Argininamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, Benzyloxycarbonylphenylalanylarginine 4-methyl-7-coumarylamide, Carbobenzoxy-<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-arginine-4-methylcoumaryl-7-amide, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-<smallcap>L</span>-argininamide, Z-Phe-Arg-AMC, Z-Phe-Arg-AMC . HCl, benzyl [(2S)-1-({(2S)-5-[(diaminomethylidene)amino]-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]pentanoyl}amino)-1-oxo-3-phenylpropan-2-yl]carbamate

Beschreibung

Z-Phe-Arg-AMC·HCl is a fluorescent substrate for proteolytic enzymes. It has been shown to be a potent inhibitor of human immunoglobulin (Ig) secretion and protein synthesis in proximal tubules of the kidney, but this inhibition is not seen in the presence of other proteases. Z-Phe-Arg-AMC·HCl also inhibits the activity of soybean trypsin and hemolytic activity. This compound also has an optimum pH of 7.5 and is characterized by intermolecular hydrogen bonding as well as hydroxyl group interactions with enzyme active sites.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 649.14 g/mol
• Formel: C₃₃H₃₆N₆O₆·HCl
• Reinheit: Min. 95%