4-Piperidin-1-yl-methyl phenylamine

CAS: 29608-05-7

Ref. 3D-FP50767

Produktinformation

• Name: 4-Piperidin-1-yl-methyl phenylamine
• Synonyme: 1-Benzyl-piperidin-4-ylamine4-(1-Piperidinylmethyl)aniline, N-benzyl-4-piperidylamine, 1-(Phenylmethyl)-4-piperidinamine, Base Form, 1-Benzylpiperidin-4-amine, N-Benzyl-4-Amino Piperidine, N-benzylpiperidin-4-amine, 1-Benzyl-4-Aminopiperidine, 1-Benzyl-piperidin-4-ylamine, 4-(Piperidin-1-Ylmethyl)Benzenamine, 4-(Piperidin-1-Ylmethyl)Aniline, 4-Piperidin-1-Ylmethyl-Phenylamine, 4-(1-Piperidinylmethyl)aniline, 4-Amino-1-benzylpiperdine, 4-Amino-1-Benzyl Piperidine

Beschreibung

4-Piperidin-1-yl-methyl phenylamine is a ligand that activates the orthosteric site of the N-methyl-D-aspartate (NMDA) receptor. It has been synthesized in high yield from ethyl bromoacetate and benzylpiperidine. This compound has been shown to be a potent inhibitor of pain in animal models, which may be due to its ability to block the NMDA receptor at clinically relevant concentrations. 4-Piperidin-1-yl-methyl phenylamine also inhibits prostate cancer cells and has anticancer activity. The drug binds to the NMDA receptor subtype NR2B with high affinity, highlighting its potential clinical relevance as an analgesic for chronic pain patients with this receptor subtype.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 190.28 g/mol
• Formel: C₁₂H₁₈N₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C12H18N2/c13-12-6-4-11(5-7-12)10-14-8-2-1-3-9-14/h4-7H,1-3,8-10,13H2
• InChI Key: InChIKey=DRYFDUUAYSVNSN-UHFFFAOYSA-N
• SMILES: Nc1ccc(CN2CCCCC2)cc1