4-(Piperazin-1-yl)-1H-indole
CAS: 84807-09-0
Ref. 3D-FP63534
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Produktinformation
- 4-(Piperazino)indole
- 1-(1H-Indol-4-yl)piperazine
- 1-(4-Indolyl)piperazine
- 1H-Indole, 4-(1-piperazinyl)-
- 4-(1-Piperazinyl)-1H-indole
- 4-(piperazin-1-yl)-1H-indole
4-(Piperazin-1-yl)-1H-indole is a compound that is used to study the function of serotonin receptors. It has been shown to have antidepressant-like activity in animal models and has been reported as an analog of 5-HT1A receptor agonists. This compound also has potent dopamine reuptake inhibition, which may be due to its ability to bind to the dopamine transporter in the presynaptic membrane. 4-(Piperazin-1-yl)-1H-indole has been shown to have a pharmacophore with a specific arrangement of functional groups that resemble those found in SSRIs (selective serotonin reuptake inhibitors). Computational methods were used to search for new compounds with similar pharmacological properties.