Picropodophyllin

CAS: 477-47-4

Ref. 3D-FP63882

Produktinformation

• Name: Picropodophyllin
• Synonyme: (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
• Marke: Biosynth
• Beschreibung: Picropodophyllin is a semi-synthetic small molecule compound, which is derived from the natural podophyllotoxin isolated from the roots of Podophyllum species. It functions primarily as an insulin-like growth factor-1 receptor (IGF-1R) inhibitor, disrupting downstream signaling pathways that are essential for cellular proliferation and survival. By selectively inhibiting IGF-1R, picropodophyllin interferes with critical cellular processes, such as DNA synthesis and cell cycle progression, which are vital in oncogenic transformation.

Chemische Eigenschaften

• Molekulargewicht: 414.41 g/mol
• Formel: C₂₂H₂₂O₈
• Reinheit: Min. 95%
• Farbe/Form: White Powder