SB-649868

CAS: 380899-24-1

Ref. 3D-FQA89924

Produktinformation

• Name: SB-649868
• CAS: 380899-24-1

Beschreibung

SB-649868 is a drug in clinical development for the treatment of sleep-wake disorders. It is a potent and selective allosteric modulator of the GABAA receptor, with a profile that includes high affinity for the α1β2γ2 subtype. SB-649868 has been shown to increase slow wave sleep and delta power during wakefulness in healthy human subjects. SB-649868 has also been shown to have no effect on blood pressure or heart rate at clinically relevant doses, suggesting reduced risk for cardiovascular side effects.
SB-649868 was well tolerated in preclinical studies, without serious adverse events observed.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 477.55 g/mol
• Formel: C₂₆H₂₄FN₃O₃S
• Reinheit: Min. 95%