13-cis-Retinoic acid

CAS: 4759-48-2

Ref. 3D-FR27714

Produktinformation

• Name: 13-cis-Retinoic acid
• Synonyme: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2Z,4E,6E,8E-nonatetranenoic acidIsotretinoin13-cis-Vitamin A acid
• Marke: Biosynth
• Beschreibung: An endogenous retinoic acid receptor (RAR) agonist that upregulates forkhead box class O (FoxO) transcription factor. Suppresses activity and proliferation of sebaceous glands. Used for treating nodulocystic acne. Induces differentiation, neurite outgrowth and inhibits proliferation of neuroblastoma cells. A potential chemopreventive agent in non-small cell lung cancer, head and neck squamous cell carcinoma and neuroblastoma.

Chemische Eigenschaften

• Molekulargewicht: 300.44 g/mol
• Formel: C₂₀H₂₈O₂
• Reinheit: Min. 97 Area-%
• Farbe/Form: Yellow Powder
• InChl: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
• InChI Key: InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N
• SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C\C(=O)O)C(C)(C)CCC1