Ralfinamide

CAS: 133865-88-0

Ref. 3D-FR98311

Produktinformation

• Name: Ralfinamide
• Synonyme: (2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide, (S)-2-[[4-[(2-Fluorobenzyl)oxy]benzyl]amino]propanamide, N~2~-{4-[(2-fluorobenzyl)oxy]benzyl}-L-alaninamide, Priralfinamide, Propanamide, 2-[[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]amino]-, (2S)-, Propanamide, 2-[[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]amino]-, (S)-

Beschreibung

Ralfinamide is a potent and selective blocker of the neuronal sodium channel. It has been shown to inhibit viral replication in cells infected with HIV-1, HSV-2, and vesicular stomatitis virus. Ralfinamide also produces a dose-dependent inhibition of rotarod performance in mice and inhibits acid formation in rat stomachs. This drug has been shown to have pressor effects at high doses and causes whole-cell recordings from neurons to be more sensitive to depolarization by an increase in intracellular chloride ions. Ralfinamide mesylate is a crystalline polymorph that is more soluble than ralfinamide hydrochloride, making it more suitable for oral administration.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 302.34 g/mol
• Formel: C₁₇H₁₉FN₂O₂
• Reinheit: Min. 95%