Succinyl coenzyme A sodium

CAS: 108347-97-3

Ref. 3D-FS160955

Produktinformation

• Name: Succinyl coenzyme A sodium
• Synonyme: Coenzyme A, S-(hydrogen butanedioate), sodium salt, disodium 1-{(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-[(hydroxyphosphinato)oxy]tetrahydrofuran-2-yl}-3,5,9-trihydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphadocosan-22-oate 3,5-dioxide (non-preferred name)

Beschreibung

Succinyl coenzyme A sodium (SCCA) is a membrane-permeable probe that can be used to measure the mitochondrial membrane potential. SCCA is transported into mitochondria and reduced by dehydrogenase, resulting in an increase in the concentration of its oxidized form, succinic semialdehyde. This increase in extracellular concentrations of succinic semialdehyde can be detected using high performance liquid chromatography with fluorescence detection. The use of this probe has been shown to be useful for measuring mitochondrial function in live cells and tissues, and for investigating genetic disorders that affect mitochondrial function.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 889.59 g/mol
• Formel: C₂₅H₄₀N₇O₁₉P₃S•Nax
• Reinheit: Min. 95%