Sorafenib N-oxide

CAS: 583840-03-3

Ref. 3D-FS27857

Produktinformation

• Name: Sorafenib N-oxide
• Synonyme: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide 1-oxide
• Marke: Biosynth
• Beschreibung: Sorafenib N-oxide is a potent anti-angiogenic agent that inhibits the growth and proliferation of new blood vessels. It has been shown to inhibit the production of epidermal growth factor, which plays an important role in the formation of new blood vessels. Sorafenib N-oxide also induces apoptosis in cancer cells by inhibiting cell factor and stem cell factor, which are necessary for cell survival. This drug has been shown to be effective against metastatic colorectal cancer in animal models, as well as renal cell cancer in humans. Sorafenib N-oxide also causes mitochondrial membrane depolarization, leading to cell death. In addition, this drug has antiangiogenic properties and inhibits the Mcl-1 protein.

Chemische Eigenschaften

• Molekulargewicht: 480.82 g/mol
• Formel: C₂₁H₁₆ClF₃N₄O₄
• Reinheit: Min. 95%
• Farbe/Form: Beige Powder