sulfo-Succinimidyl-3(4-hydroxyphenyl)propionate

CAS: 106827-57-0

Ref. 3D-FS52767

Produktinformation

• Name: sulfo-Succinimidyl-3(4-hydroxyphenyl)propionate
• Synonyme: sulfo-SHPP, Sulfosuccinimidyl-3-(4-Hydroxyphenyl) Propionate, Water-Soluble Bolton-Hunter Reagent, Sulphosuccinimidyl-3-(4-hydroxyphenyl)propionate sodium salt, Sodium 1-[3-(4-Hydroxyphenyl)Propanoyloxy]-2,5-Dioxo-Pyrrolidine-3-Sulfonate

Beschreibung

Sulfo-Succinimidyl-3(4-hydroxyphenyl)propionate (Sulforhodamine) is a molecule that can be taken up by cells. It is used to stain cells in culture and to detect uptake of the molecule in living cells. Sulforhodamine binds to the cell membrane and is taken up by acidified endosomes, where it accumulates in lysosomes. The fluorescent properties of sulforhodamine allow it to be used as a marker for cellular uptake. Sulforhodamine has been shown to inhibit human chronic myeloid leukemia cell growth, but not in other types of cancer. Sulforhodamine can also be used as a marker for epidermal growth factor receptor (EGFR) activation, which is important for regulating cell growth and differentiation.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 365.29 g/mol
• Formel: C₁₃H₁₂NSO₈Na
• Reinheit: Min. 95%