2-Thiouracil

CAS: 141-90-2

Ref. 3D-FT02604

Produktinformation

• Name: 2-Thiouracil
• Synonyme: 4-Hydroxy-2-mercaptopyrimidine, 2,3-Dihydro-2-Thioxo-4(1H)-Pyrimidino, 2,3-Dihydro-2-thioxo-4(1H)-pyrimidinone, 2-Mercapto-3H-pyrimidin-4-one, 2-Mercapto-4-hydroxypyrimidine, 2-Mercapto-4-pyrimidinol, 2-Mercapto-4-pyrimidinone, 2-Sulfanyl-3,4-dihydropyrimidin-4-one, 2-Sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one, 2-Sulfanylidene-1H-pyrimidin-4-one, 2-Sulfanylpyrimidin-4-ol, 2-Thiouracile, 2-Thioxo-2,3-dihydro-1H-pyrimidin-4-one, 2-Thioxo-2,3-dihydropyrimidin-4(1H)-one, 2-Tiouracilo, 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-, 4-Hydroxy-2-Mercaptopyrimidine, 4-Hydroxy-2-pyrimidinethiol, 6-Hydroxy-2-mercaptopyrimidine, Antagothyroil, Deracil, Nobilen, Nsc 19473, Nsc 290412, Nsc 290413, Nsc 290414, Thiouracil, Uracil, 2-Thio-

Beschreibung

2-Thiouracil is a photochemical that reacts with DNA by intermolecular hydrogen bonding, leading to DNA strand breakage. The reaction mechanism of 2-thiouracil has been elucidated through in vitro assays, which showed that the drug binds to the major groove of DNA duplexes and causes cleavage in the region containing two nitrogen atoms.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 128.15 g/mol
• Formel: C₄H₄N₂OS
• Reinheit: Min. 98 Area-%
• Farbe/Form: Powder