Trelagliptin

CAS: 865759-25-7

Ref. 3D-FT103486

Produktinformation

• Name: Trelagliptin
• Synonyme: (R)-2-[[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]methyl]-4-fluorobenzonitrile, 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile, (R)-2-[[6-(3-AMinopiperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl]Methyl]-4-fluorobenzonitrile, Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluoro-

Beschreibung

Trelagliptin is a potent, selective and orally active agonist of the glucagon-like peptide-1 receptor (GLP-1R) that improves glucose homeostasis in patients with type 2 diabetes. Trelagliptin has been shown to increase insulin secretion and reduce postprandial hyperglycemia. The drug binds to GLP-1Rs on the surface of beta cells in the pancreas. This binding stimulates cAMP production, leading to increased insulin release from pancreatic beta cells. Trelagliptin is chemically stable in human serum, exhibiting no significant changes after incubation for up to 72 hours at 37°C.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 357.38 g/mol
• Formel: C₁₈H₂₀FN₅O₂
• Reinheit: Min. 95%