(5S)-3,4,5,6-Tetrahydro-5-phenyl-4(h)-1,4-oxazin-2-one
CAS: 144896-92-4
Ref. 3D-FT148618
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Produktinformation
- (5S)-3,4,5,6-Tetrahydro-5-Phenyl-2(H)-1,4-Oxazin-2-One
- S-5-Phenyl-Morpholin-2-One
- (5S)-3,4,5,6-(S)-5-Phenylmorpholin-2-one
- (5S)-5-phenylmorpholin-2-one
The asymmetric synthesis of (5S)-3,4,5,6-Tetrahydro-5-phenyl-4(h)-1,4-oxazin-2-one has been accomplished by a 1,3-dipolar cycloaddition of an iminium ion with a chiral aliphatic aldehyde. The diastereoselectivity was controlled by the transition state geometry and stereochemical outcome of the 1,3-dipolar cycloaddition.
Aldehydes are stabilized in hydrochloric acid because of its electrophilic nature. This makes it possible to conduct asymmetric syntheses with them.
The molecule is chiral because it contains a carbon atom that has four different substituents on it. It can be classified as an enantiopure molecule because it has two enantiomers that are not superimposable on each other.