Tioclomarol

CAS: 22619-35-8

Ref. 3D-FT28286

Produktinformation

• Name: Tioclomarol
• Synonyme: 3-[3-(4-Chlorophenyl)-1-(5-chloro-2-thienyl)-3-hydroxypropyl]-4-hydroxy-2H-1-benzopyran-2-oneApegmone
• Marke: Biosynth
• Beschreibung: Tioclomarol is a drug that is used to treat severe atherosclerotic lesions in coronary heart disease. It binds to the receptor on the surface of the cardiac muscle cells, which causes an increase in intracellular cyclic adenosine monophosphate (cAMP) and a decrease in intracellular calcium. This results in relaxation of the heart tissue, which decreases blood pressure and prevents plaque formation. Tioclomarol also has been shown to prevent heparin-induced thrombocytopenia by binding to platelets and preventing their aggregation. Tioclomarol has been found to inhibit cellular proliferation in some types of cancer cells, but not others.

Chemische Eigenschaften

• Molekulargewicht: 447.33 g/mol
• Formel: C₂₂H₁₆Cl₂O₄S
• Reinheit: Min. 95 Area-%
• Farbe/Form: Powder
• InChl: InChI=1S/C22H16Cl2O4S/c23-13-7-5-12(6-8-13)16(25)11-15(18-9-10-19(24)29-18)20-21(26)14-3-1-2-4-17(14)28-22(20)27/h1-10,15-16,25-26H,11H2
• InChI Key: InChIKey=WRGOVNKNTPWHLZ-UHFFFAOYSA-N
• SMILES: O=c1oc2ccccc2c(O)c1C(CC(O)c1ccc(Cl)cc1)c1ccc(Cl)s1