Trabectedin

CAS: 114899-77-3

Ref. 3D-FT28354

Produktinformation

• Name: Trabectedin
• Synonyme: (1'R,6R,6aR,7R,13S,14S,16R)-5-(Acetyloxy)-3',4',6,6a,7,13,14,16-octahydro-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-spiro[ 6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinolin]-19
• Marke: Biosynth
• Beschreibung: Trabectedin is a model system for investigating the role of protein genes in cancer. It is used for high throughput screening of potential biomarkers, such as blood sampling and mouse tumor models. Trabectedin has been shown to be a potent inhibitor of the p-gp substrate and has been used in vivo to treat cancers, including solid tumors and experimental models. This drug was also found to inhibit the antitumor response in normal human cells. Trabectedin is a taxane derivative that binds to the surface of cells with high affinity and prevents phosphorylation of proteins on the cell surface, which leads to inhibition of cell proliferation.

Chemische Eigenschaften

• Molekulargewicht: 761.84 g/mol
• Formel: C₃₉H₄₃N₃O₁₁S
• Reinheit: Min. 95%
• Farbe/Form: White/Off-White Solid