O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine

CAS: 680622-70-2

Ref. 3D-FT28439

Produktinformation

• Name: O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine
• Synonyme: N-[4-(2-Amino-9H-purin-6-yloxymethyl)-benzyl]-2,2,2-trifluoroacetamide

Beschreibung

O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine is a modified nucleoside that is an inhibitor of microRNAs (miRNAs). It can be used as a therapeutic agent for the treatment of cancer. O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine is orally bioavailable and has shown tumor inhibition in invertebrate models. It is stable in vivo and has been shown to inhibit the activity of miRNA-1, miRNA-2, and miRNA-29b. This molecule also provides optimal orientation for highlighting through its large size, which makes it suitable for use with electron microscopy.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 366.3 g/mol
• Formel: C₁₅H₁₃F₃N₆O₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C15H13F3N6O2/c16-15(17,18)13(25)20-5-8-1-3-9(4-2-8)6-26-12-10-11(22-7-21-10)23-14(19)24-12/h1-4,7H,5-6H2,(H,20,25)(H3,19,21,22,23,24)
• InChI Key: InChIKey=AQFWAWXGBQPBIA-UHFFFAOYSA-N
• SMILES: Nc1nc(OCc2ccc(CNC(=O)C(F)(F)F)cc2)c2[nH]cnc2n1