Trihydroxycoprostane

CAS: 547-96-6

Ref. 3D-FT28498

Produktinformation

• Name: Trihydroxycoprostane
• Synonyme: (3a,5b,7a,12a)-Cholestane-3,7,12-triol3a,7a,12a-Trihydroxycoprostane, (3alpha,5beta,7alpha,12alpha)-Cholestane-3,7,12-triol, 5β-Cholestane-3α,7α,12α-triol, 3α,7α,12α-Trihydroxycoprostane, Cholestane-3,7,12-triol, (3α,5β,7α,12α)-, (3α,5β,7α,12α)-Cholestane-3,7,12-triol

Beschreibung

Trihydroxycoprostane is a natural compound and metabolite of cholesterol. It is produced by the microsomal cytochrome P450 enzymes in the liver, where it is converted to dihydroxycoprostane. Trihydroxycoprostane has been found to be a precursor of acid formation in humans, which may be due to its conversion to p-hydroxyphenylacetaldehyde and then to p-hydroxyphenylacetic acid. The uptake, metabolism and excretion of trihydroxycoprostanes have been studied in human liver cells and rat liver microsomes. This study found that trihydroxycoprostanes are metabolized by 3β-HSD or 3α-HSD and converted into dihydroxycoprostanes. Trihydroxycoprostane has also been shown to increase serum levels of alanine and urea nitrogen, but does not affect cholesterol levels in rats with cerebrotendinous xanthomat

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 420.67 g/mol
• Formel: C₂₇H₄₈O₃
• Reinheit: Min. 95%