2,4,4'-Trihydroxybenzophenone

CAS: 1470-79-7

Ref. 3D-FT30132

Produktinformation

• Name: 2,4,4'-Trihydroxybenzophenone
• Synonyme: (2,4-Dihydroxyphenyl)(4-Hydroxyphenyl)Methanone, 2,4-Dihydroxyphenyl p-hydroxybenzyl ketone, Benzophenone, 2,4,4′-trihydroxy-, Methanone, (2,4-dihydroxyphenyl)(4-hydroxyphenyl)-, NSC 76052

Beschreibung

2,4,4'-Trihydroxybenzophenone is a synthetic compound that has been shown to have receptor binding properties. It also inhibits the effects of estradiol by competitively binding to the estrogen receptors α and β in the presence of estradiol. 2,4,4'-Trihydroxybenzophenone has been found to exert a variety of health effects including carcinogenic and genotoxic effects. These effects are mediated through its ability to bind with DNA and affect the expression of genes. The uv irradiation can cause the formation of reactive oxygen species in cells which can lead to DNA damage. 2,4,4'-Trihydroxybenzophenone also has an estrogenic effect on human breast cancer cells in vitro as well as estrogen-dependent mammary tumors in rats. This agent binds with high affinity to estrogen receptors α and β.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 230.22 g/mol
• Formel: C₁₃H₁₀O₄
• Reinheit: Min. 95%
• Farbe/Form: White To Light (Or Pale) Yellow Solid
• InChl: InChI=1S/C13H10O4/c14-9-3-1-8(2-4-9)13(17)11-6-5-10(15)7-12(11)16/h1-7,14-16H
• InChI Key: InChIKey=OKJFKPFBSPZTAH-UHFFFAOYSA-N
• SMILES: O=C(c1ccc(O)cc1)c1ccc(O)cc1O