Tenofovir alafenamide (free base)

CAS: 379270-37-8

Ref. 3D-FT76562

Produktinformation

• Name: Tenofovir alafenamide (free base)
• Synonyme: <span class="text-smallcaps">L</span>-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, Gs-7340, Tenofovir Alafenamide, Tenofovir Alafenamide free base, Vemlidy, L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, 4: PN: WO2016077321 SEQID: 4 claimed sequence

Beschreibung

Tenofovir alafenamide is a prodrug of tenofovir, which is an acyclic nucleoside phosphonate that inhibits viral replication by inhibiting the viral polymerase. Tenofovir alafenamide is a prodrug of tenofovir, which is an acyclic nucleoside phosphonate that inhibits viral replication by inhibiting the viral polymerase. Tenofovir alafenamide has shown to be less toxic than tenofovir in preclinical studies and can be used as an oral prodrug for the treatment of HIV-1 infection. The pharmacokinetics of tenofovir alafenamide have been studied in a model system that simulates human exposure to this drug. A concentration-time curve was generated and a mathematical model created to describe the pharmacokinetics of tenofovir alafenamide. The active form of tenofovir, tenofovir disoprox

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 476.47 g/mol
• Formel: C₂₁H₂₉N₆O₅P
• Reinheit: Min. 97 Area-%
• Farbe/Form: Powder