Valerophenone
CAS: 1009-14-9
Ref. 3D-FV173268
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Produktinformation
- 1-Pentanone, 1-phenyl-
- 1-Phenyl-1-pentanone
- Benzene, Pentanoyl-
- Butyl phenyl ketone
- Nsc 58959
- Pentanophenone
- Phenyl butyl ketone
- Valerofenona
- Valerophenon
- n-Butyl phenyl ketone
- Mehr Synonyme anzeigen
- n-Valerophenone
Valerophenone is a trifluoroacetic acid (TFA) derivative that is used as a potent antagonist of the histamine H1 receptor. Valerophenone binds to the receptor cells and blocks the action of histamine, thereby inhibiting the release of other mediators such as prostaglandins and leukotrienes. This drug has shown strong inhibitory effects on polymerase chain reaction (PCR), chemiluminescent reactions, and analytical methods such as constant pressure. It also inhibits substrate film formation, which can lead to increased light emission in chemiluminescent reactions. Valerophenone has been shown to be an effective inhibitor of human recombinant histamine H1 receptors at concentrations below 10 μM. The mechanism of this inhibition is thought to be due to its ability to form intramolecular hydrogen bonds with the hydroxyl group located at C-5 on the benzene ring.
Chemische Eigenschaften
Technische Anfrage zu: 3D-FV173268 Valerophenone
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